Article
B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2005
Hurchla Michelle A, Sedy John R, Gavrieli Maya, Gavrielli Maya, Drake Charles G, Murphy Theresa L, Murphy Kenneth M
Abstract excerpt
B and T lymphocyte attenuator (BTLA) was initially identified as expressed on Th1 cells and B cells, but recently reported to be expressed by macrophages, dendritic cells, and NK cells as well. To address this discrepancy we generated a panel of BTLA-specific mAbs and characterized BTLA expression under various activation conditions. We report the existence of three distinct BTLA alleles among 23 murine strains,...
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