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Article

Phenotypic characterisation of mice with exaggerated and missing LH/hCG action.

Molecular and cellular endocrinology - 2 Jan 2007

Ahtiainen Petteri, Rulli Susana, Pakarainen Tomi, Zhang Fu-Ping, Poutanen Matti, Huhtaniemi Ilpo

Abstract excerpt

In order to study the physiology and pathophysiology of gonadotrophin action, we have produced transgenic (TG) mice overexpressing human chorionic gonadotrophin (hCG) alpha and beta subunits (hCG+ mice) and knockout (KO) mice for the luteinising hormone receptor (LHR; LuRKO mice). The two extremes in LH function, i.e. strong LH/hCG stimulation and total blockade of this action, confirm numerous earlier concepts...

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Identifiers

PMID: 17029767
DOI: 10.1016/j.mce.2005.11.047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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