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Article

Genetic Models for the Study of Luteinizing Hormone Receptor Function

29 Sept 2015

Abstract excerpt

The luteinizing hormone/chorionic gonadotropin receptor (LHCGR) is essential for fertility in men and women. LHCGR binds luteinizing hormone (LH) as well as the highly homologous chorionic gonadotropin. Signaling from LHCGR is required for steroidogenesis and gametogenesis in males and females and for sexual differentiation in the male. The importance of LHCGR in reproductive physiology is underscored by the...

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Identifiers

PMID: 26483755
DOI: 10.3389/fendo.2015.00152

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