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Article

Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome.

Molecular immunology - 1 Mar 2007

Liszewski M Kathryn, Leung Marilyn K, Schraml Barbara, Goodship Timothy H J, Atkinson John P

Abstract excerpt

Mutations in complement regulatory proteins predispose to the development of aHUS. Approximately 50% of patients bear a mutation in one of three complement control proteins, factor H, factor I, or membrane cofactor protein (MCP; CD46). Another membrane regulator that is closely related to MCP, de...

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Identifiers

PMID: 17027083
DOI: 10.1016/j.molimm.2006.08.024
PMCID: PMC1828070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17027083-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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