Article
Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome.
Molecular immunology - 1 Jan 2007
Richards Anna, Kathryn Liszewski M, Kavanagh David, Fang Celia J, Moulton Elizabeth, Fremeaux-Bacchi Veronique, Remuzzi Giuseppe, Noris Marina, Goodship Timothy H J, Atkinson John P
Abstract excerpt
The hemolytic uremic syndrome is characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. There are two general types. One occurs in epidemic form and is diarrheal associated (D+HUS). It has a good prognosis. The second is a rare form known as aty...
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