Article
Molecular biology of antibiotic production in Bacillus.
Critical reviews in biotechnology - 1 Jan 1990
Nakano M M, Zuber P
Abstract excerpt
Several species of the genus Bacillus produce peptide antibiotics which are synthesized either through a ribosomal or non-ribosomal mechanism. The antibiotics gramicidin, tyrocidine, and bacitracin are synthesized nonribosomally by the multienzyme thiotemplate mechanism. Surfactin and mycobacillin are also synthesized nonribosomally but by a mechanism that, apparently, is distinct from that of the multienzyme...
Topics
- Amino Acid Sequence
- Anti-Bacterial Agents
- Bacillus
- Bacterial Proteins
- Base Sequence
- Gramicidin
- Lipopeptides
- Molecular Sequence Data
- Mutation
- Peptides, Cyclic
- Ribosomes
- Tyrocidine