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Do mutations in Plasmodium falciparum dihydropteroate synthase and dihydrofolate reductase confer resistance to sulfadoxine-pyrimethamine in Iran?

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000

Eskandarian Abbas-Ali, Keshavarz Hossein, Basco Leonardo K, Mahboudi Fereidoun

Abstract excerpt

The key codons of dihydropteroate synthase (dhps) and dihydrofolate reductase (dhfr) genes implicated in sulfadoxine-pyrimethamine (SP) resistance were determined by allele-specific polymerase chain reaction in Plasmodium falciparum isolates collected in 1999 from 35 Iranian patients treated with...

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Identifiers

PMID: 11926005
DOI: 10.1016/s0035-9203(02)90254-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11926005-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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