Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Ia (HLA-DR) and low CD11b (Mo1) expression may predict early conversion to leukemia in myelodysplastic syndromes.

American journal of hematology - 1 Jul 1993

Mittelman M, Karcher D S, Kammerman L A, Lessin L S

Abstract excerpt

The FAB classification of myelodysplastic syndromes (MDS) has been useful in predicting prognosis; however, additional methods are required to detect patients at high risk for early conversion to acute nonlymphoblastic leukemia (ANLL). Using a panel of monoclonal antibodies to myelomonocytic surf...

Topics

Adult
Aged
Aged, 80 and over
Antibodies, Monoclonal
Antigens, Surface
Bone Marrow Cells
Cell Transformation, Neoplastic
Female
HLA-DR Antigens
Humans
Leukemia
Macrophage-1 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Myelodysplastic Syndromes

Phenotype

Prognosis

Source

Identifiers

PMID: 8352230
DOI: 10.1002/ajh.2830430302

Genes

TTL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8352230-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

High Ia (HLA-DR) and low CD11b (Mo1) expression may predict early conversion to leukemia in myelodysplastic syndromes.PMID 8352230Read ↗

Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans.Semantic proximity Read ↗

Immunophenotypic characterization of myelopoiesis in early and late myelodysplastic syndromes: use of CD44 as an aid in early diagnosis.Semantic proximity Read ↗

Immunophenotypic aberrant hematopoietic stem cells in myelodysplastic syndromes: a biomarker for leukemic progressionSemantic proximity Read ↗

Predicting which subsets of patients with myelodysplastic neoplasms are more likely to progress to overt chronic myelomonocytic leukemia.Semantic proximity Read ↗

Flow Cytometry Rapidly Identifies All Acute Promyelocytic Leukemias With High Specificity Independent of Underlying Cytogenetic AbnormalitiesSemantic proximity Read ↗

Evidence for reduced B-cell progenitors in early (low-risk) myelodysplastic syndromeSemantic proximity Read ↗

[New insights into the nature and classification of myelodysplastic neopmasm].Semantic proximity Read ↗

Myeloblast phenotypic changes in myelodysplasia. CD34 and CD117 expression abnormalities are common.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.