Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of glypican-1 expression with TGF-β, BMP, and activin receptors in pancreatic ductal adenocarcinoma

1 Nov 2006

Abstract excerpt

Glypican1 (GPC1) is a cell surface heparan sulfate proteoglycan that acts as a co-receptor for heparin-binding growth factors as well as for members of the TGF-beta family. GPC1 plays a role in pancreatic cancer by regulating growth factor responsiveness. In view of the importance of members of the TGF-beta family in pancreatic cancer, in the present study, the role of GPC1 in TGF-beta, BMP and activin signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hedgehog Signaling Pathway Studies
Share to Pancreatic and Hepatic Oncology Research
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17016645
DOI: 10.3892/ijo.29.5.1139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of glypican-1 expression with TGF-β, BMP, and activin receptors in pancreatic ductal adenocarcinomaPMID 17016645Read ↗

GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathwaySemantic proximity Read ↗

Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells.Semantic proximity Read ↗

FOXC1 plays a crucial role in the growth of pancreatic cancerSemantic proximity Read ↗

CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells.Semantic proximity Read ↗

Tumor -Associated MUC1 Regulates TGF-β Signaling and Function in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progressionSemantic proximity Read ↗

Identification of FOXC1 as a TGF-β1 Responsive Gene and Its Involvement in Negative Regulation of Cell GrowthSemantic proximity Read ↗

Bone morphogenetic protein -4 and -5 in pancreatic cancer--novel bidirectional players.Semantic proximity Read ↗

RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells.Semantic proximity Read ↗

Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of actionSemantic proximity Read ↗

Transforming growth factor-beta responsiveness in DPC4/SMAD4-null cancer cells.Semantic proximity Read ↗

Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.