Article
Pro-oxidative effects of tea and polyphenols, epigallocatechin-3-gallate and epigallocatechin, on G6PD-deficient erythrocytes in vitro.
International journal of molecular medicine - 1 Nov 2006
Ko Chun Hay, Li Karen, Ng Pak Cheung, Fung Kwok Pui, Li Chung Leung, Wong Raymond Pui-On, Chui Kit Man, Gu Goldie Jia-Shi, Yung Edmund, Wang Chi Chiu, Fok Tai Fai
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD)-deficient subjects are vulnerable to chemical-induced hemolysis if exposed to oxidative agents. Recent studies reported that green tea and its constituents might act as pro-oxidants. Our objective was to investigate effects of tea and its polyphenolic components on the oxidative status of human G6PD-deficient erythrocytes. Erythrocytes of G6PD-deficient (n = 8) and normal...
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