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Article

TEGDMA modulates glutathione transferase P1 activity in gingival fibroblasts.

Journal of dental research - 1 Dec 2004

Lefeuvre M, Bourd K, Loriot M-A, Goldberg M, Beaune P, Périanin A, Stanislawski L

Abstract excerpt

Dental resinous materials can contain large amounts (from 30 to 50%) of triethylene-glycol-dimethacrylate (TEGDMA). This compound leaches into aqueous media and is toxic to dental pulp, as well as to gingival fibroblasts in vitro. To elucidate the mechanism of TEGDMA toxicity, we investigated the effects on glutathione (GSH) level and glutathione transferase P1 (GSTP1) activity in cultured human gingival...

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Source

Identifiers

PMID: 15557397
DOI: 10.1177/154405910408301205

Genes

GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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