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Article

Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells

2 Oct 2006

Abstract excerpt

Androgen receptor (AR) protein expression and function are critical for survival and proliferation of androgen-sensitive (AS) prostate cancer cells. Besides its ability to function as a transcription factor, experimental observations suggest that AR becomes a licensing factor for DNA replication in AS prostate cancer cells and thus must be degraded during each cell cycle in these cells to allow reinitiation of...

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Share to Estrogen and related hormone effects
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Identifiers

PMID: 17015840
DOI: 10.1073/pnas.0603057103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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