Article
Differential expression of CD11c by peripheral blood NK cells reflects temporal activity of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2006
Aranami Toshimasa, Miyake Sachiko, Yamamura Takashi
Abstract excerpt
Multiple sclerosis (MS) is an autoimmune disease, showing a great degree of variance in temporal disease activity. We have recently demonstrated that peripheral blood NK cells biased for secreting IL-5 (NK2 bias) are associated with the remission state of MS. In this study, we report that MS patients in remission differentially express CD11c on NK cell surface (operationally defined as CD11chigh or CD11clow)....
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