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Article

Analyses of phenotypic and functional characteristics of CX3CR1-expressing natural killer cells.

Immunology - 1 May 2011

Hamann Isabell, Unterwalder Nadine, Cardona Astrid E, Meisel Christian, Zipp Frauke, Ransohoff Richard M, Infante-Duarte Carmen

Abstract excerpt

We previously demonstrated a correlation between the frequency of CX3CR1-expressing human natural killer (NK) cells and disease activity in multiple sclerosis and showed that CX3CR1(high) NK cells were more cytotoxic than their CX3CR1(neg/low) counterparts. Here we aimed to determine whether human NK cell fractions defined by CX3CR1 represent distinct subtypes. Phenotypic and functional NK cell analyses revealed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21320123
DOI: 10.1111/j.1365-2567.2011.03409.x
PMCID: PMC3088968

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