Article
Versatility and differential roles of cysteine residues in human prostacyclin receptor structure and function.
The Journal of biological chemistry - 1 Dec 2006
Stitham Jeremiah, Gleim Scott R, Douville Karen, Arehart Eric, Hwa John
Abstract excerpt
Prostacyclin plays important roles in vascular homeostasis, promoting vasodilatation and inhibiting platelet thrombus formation. Previous studies have shown that three of six cytoplasmic cysteines, particularly those within the C-terminal tail, serve as important lipidation sites and are differen...
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