Article
Age-related changes in visual acuity, learning and memory in C57BL/6J and DBA/2J mice.
Neurobiology of aging - 1 Oct 2007
Wong Aimée A, Brown Richard E
Abstract excerpt
The DBA/2J mouse is a model of age-related pigmentary glaucoma in humans. Visual detection, pattern discrimination and visual acuity were evaluated in DBA/2J, C57BL/6J, B6.mpc1d (a C57 congenic strain) and D2.mpc1b (a D2 congenic strain) mice at 6, 12, 18 and 24 months of age. Mice were also tested in the Morris Water Maze and olfactory discrimination learning task. At 6 months, DBA/2J and D2.mpc1b mice...
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