Article
Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach.
BMC genomics - 29 Sept 2006
Bainbridge Matthew N, Warren René L, Hirst Martin, Romanuik Tammy, Zeng Thomas, Go Anne, Delaney Allen, Griffith Malachi, Hickenbotham Matthew, Magrini Vincent, Mardis Elaine R, Sadar Marianne D, Siddiqui Asim S, Marra Marco A, Jones Steven J M
Abstract excerpt
BACKGROUND: High throughput sequencing-by-synthesis is an emerging technology that allows the rapid production of millions of bases of data. Although the sequence reads are short, they can readily be used for re-sequencing. By re-sequencing the mRNA products of a cell, one may rapidly discover polymorphisms and splice variants particular to that cell. RESULTS: We present the utility of massively parallel...
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