Article
Association between gene polymorphisms of SLC22A3 and methamphetamine use disorder.
Alcoholism, clinical and experimental research - 1 Oct 2006
Aoyama Nagisa, Takahashi Nagahide, Kitaichi Kiyoyuki, Ishihara Ryoko, Saito Shinichi, Maeno Nobuhisa, Ji Xiaofei, Takagi Kenji, Sekine Yoshimoto, Iyo Masaomi, Harano Mutsuo, Komiyama Tokutaro, Yamada Mitsuhiko, Sora Ichiro, Ujike Hiroshi, Iwata Nakao, Inada Toshiya, Ozaki Norio
Abstract excerpt
BACKGROUND: Methamphetamine (MAP) is one of the most frequently used illegal substances in Japan, and family and twin studies have suggested that genetic factors contribute to psychostimulant dependence, including MAP dependence. Organic cation transporter 3 (OCT3) has been reported to be involved in the disposition of MAP as well as MAP-induced behavioral changes in animals. Moreover, SLC22A3 (which encodes...
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