Article
Functional analysis of 11 putative essential genes in Bacillus subtilis.
Microbiology (Reading, England) - 1 Oct 2006
Hunt Alison, Rawlins Joy P, Thomaides Helena B, Errington Jeff
Abstract excerpt
Systematic inactivation of Bacillus subtilis genes has previously revealed that 271 are indispensable for growth. In the present study, 11 of these (yacA, ydiB, ydiC, ykqC, ylaN, yloQ, ymdA, yneS, yqeI, yqjK and ywlC) were identified as genes encoding proteins of unknown function. By analysing the effects of protein depletion, and examining the subcellular localization of these proteins, a start has been made in...
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