Article
Predicting conserved essential genes in bacteria: in silico identification of putative drug targets.
Molecular bioSystems - 1 Dec 2010
Duffield Melanie, Cooper Ian, McAlister Erin, Bayliss Marc, Ford Donna, Oyston Petra
Abstract excerpt
Many genes have been listed as putatively essential for bacterial viability in the Database of Essential Genomes (DEG), although few have been experimentally validated. By prioritising targets according to the criteria suggested by the Research and Training in Tropical Diseases (TDR) Targets data...
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