SNP-based analysis of genetic substructure in the German population.

doi:10.1159/000095850

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SNP-based analysis of genetic substructure in the German population.

Human heredity - 1 Jan 2006

Steffens Michael, Lamina Claudia, Illig Thomas, Bettecken Thomas, Vogler Rainer, Entz Patricia, Suk Eun-Kyung, Toliat Mohammad Reza, Klopp Norman, Caliebe Amke, König Inke R, Köhler Karola, Ludemann Jan, Diaz Lacava Amalia, Fimmers Rolf, Lichtner Peter, Ziegler Andreas, Wolf Andreas, Krawczak Michael, Nūrnberg Peter, Hampe Jochen, Schreiber Stefan, Meitinger Thomas, Wichmann H-Erich, Roeder Kathryn, Wienker Thomas F, Baur Max P

Abstract excerpt

OBJECTIVE: To evaluate the relevance and necessity to account for the effects of population substructure on association studies under a case-control design in central Europe, we analysed three samples drawn from different geographic areas of Germany. Two of the three samples, POPGEN (n = 720) and SHIP (n = 709), are from north and north-east Germany, respectively, and one sample, KORA (n = 730), is from southern...

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PMID: 17003564
DOI: 10.1159/000095850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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