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Article

Effect of Ionizing Radiation Induced Damage of Endothelial Progenitor Cells in Vascular Regeneration

11 Nov 2011

Abstract excerpt

OBJECTIVE: A number of studies have revealed that stress signaling and subsequent stress responses in stem/progenitor cells are responsible for attenuated regeneration or degenerative disease. Because ionizing radiation (IR), which sensitizes diverse types of stem cells, reportedly induces cardio-circulatory diseases, we hypothesized that IR-induced vascular abnormalities are associated with defects in...

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PMID: 22075244
DOI: 10.1161/atvbaha.111.237651

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