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Article

Mutational analysis of the vitamin D receptor does not support its candidacy as a tumor suppressor gene in parathyroid adenomas.

The Journal of clinical endocrinology and metabolism - 1 Dec 2006

Samander Elizabeth Hanna, Arnold Andrew

Abstract excerpt

CONTEXT: The vitamin D receptor gene (VDR) is a compelling candidate tumor suppressor gene for parathyroid adenomas based on existing evidence of the vitamin D system's antiproliferative actions in parathyroid and other tissues, its reported inhibition of PTH gene transcription, and the decreased expression of VDR mRNA and VDR protein observed in parathyroid adenomas. OBJECTIVE: Because demonstration of...

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Share to Adenoma
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Hyperparathyroidism, Primary

Share to Loss of Heterozygosity

Share to Parathyroid Neoplasms

Share to Receptors, Calcitriol

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 17003089
DOI: 10.1210/jc.2006-1543

Genes

VDR
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of the vitamin D receptor does not support its candidacy as a tumor suppressor gene in parathyroid adenomas.PMID 17003089Read ↗

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