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Article

No evidence for mutations in the calcium-sensing receptor gene in sporadic parathyroid adenomas.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 1999

Cetani F, Pinchera A, Pardi E, Cianferotti L, Vignali E, Picone A, Miccoli P, Viacava P, Marcocci C

Abstract excerpt

Inactivating mutations of the calcium-sensing receptor gene (CaR) might explain abnormalities in the regulation of both parathyroid cell proliferation and parathyroid hormone secretion. In a previous study, using RNAse A protection assay, no mutations were identified in a series of parathyroid specimens from patients with primary and secondary hyperparathyroidism, but the analysis was incomplete, since part of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10352095
DOI: 10.1359/jbmr.1999.14.6.878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No evidence for mutations in the calcium-sensing receptor gene in sporadic parathyroid adenomas.PMID 10352095Read ↗

Tumor-Specific Decreased Expression of Calcium Sensing Receptor Messenger Ribonucleic Acid in Sporadic Primary Hyperparathyroidism<sup>1</sup>Semantic proximity Read ↗

Mutational analysis of the extracellular Ca(2+)-sensing receptor gene in human parathyroid tumors.Semantic proximity Read ↗

Genetic abnormalities in sporadic parathyroid adenomas: loss of heterozygosity for chromosome 3q markers flanking the calcium receptor locus.Semantic proximity Read ↗

Pancreatitis in primary hyperparathyroidism-related hypercalcaemia is not associated with mutations in the CASR gene.Semantic proximity Read ↗

Mutational analysis of the vitamin D receptor does not support its candidacy as a tumor suppressor gene in parathyroid adenomas.Semantic proximity Read ↗

Sporadic hypoparathyroidism caused by de Novo gain-of-function mutations of the Ca(2+)-sensing receptor.Semantic proximity Read ↗

Absence of stabilizing mutations of beta-catenin encoded by CTNNB1 exon 3 in a large series of sporadic parathyroid adenomas.Semantic proximity Read ↗

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Familial hypercalcemia and hypercalciuria: no mutations in the Ca2+-sensing receptor gene.Semantic proximity Read ↗

Mutational analysis of the extracellular Ca(2+)-sensing receptor gene in human parathyroid tumorsSemantic proximity Read ↗

Cloning and Characterization of Two Promoters for the Human Calcium-sensing Receptor (CaSR) and Changes of CaSR Expression in Parathyroid AdenomasSemantic proximity Read ↗

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