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Article

Hormonal activity of AIMP1/p43 for glucose homeostasis.

Proceedings of the National Academy of Sciences of the United States of America - 3 Oct 2006

Park Sang Gyu, Kang Young Sun, Kim Jin Young, Lee Chang Seok, Ko Young Gyu, Lee Woo Je, Lee Ki-Up, Yeom Young Il, Kim Sunghoon

Abstract excerpt

AIMP1/p43 is known as a cytokine working in the control of angiogenesis, inflammation, and wound healing. Here we report its enrichment in pancreatic alpha cells and glucagon-like hormonal activity. AIMP1 is secreted from the pancreas upon glucose starvation. Exogenous infusion of AIMP1 increased plasma levels of glucose, glucagon, and fatty acid, and AIMP1-deficient mice showed reduced plasma glucose levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17001013
DOI: 10.1073/pnas.0602045103
PMCID: PMC1595450

Genes

AIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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