Article
A multiplex single-base extension protocol for genotyping Cdx2, FokI, BsmI, ApaI, and TaqI polymorphisms of the vitamin D receptor gene.
Genetics and molecular research : GMR - 22 May 2007
Lins T C L, Nogueira L R, Lima R M, Gentil P, Oliveira R J, Pereira R W
Abstract excerpt
The well-described role of the vitamin D endocrine system in bone metabolism makes its receptor a widely investigated candidate gene in association studies looking for the genetic basis of complex bone-related phenotypes. Most association studies genotype five polymorphic sites along the gene using PCR-RFLP and allele-specific amplification methods, which may not be the better choice in large case/control or...
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