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Article

Raising the curtains on interchromosomal interactions.

Trends in genetics : TIG - 1 Dec 2006

Krueger Christel, Osborne Cameron S

Abstract excerpt

The chromosome conformation capture technique is used to monitor intra- and intermolecular chromosomal associations. By introducing an adaptation of this technique, Ling and colleagues have identified an unexpected coassociation between two loci on separate chromosomes in mouse nuclei, the imprinted Igf2-H19 locus of chromosome 7 and the Wsb1-Nf1 locus of chromosome 11. Strikingly, this interaction is...

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Source

Identifiers

PMID: 16997416
DOI: 10.1016/j.tig.2006.09.008

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Raising the curtains on interchromosomal interactions.PMID 16997416Read ↗

CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1.Semantic proximity Read ↗

Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development.Semantic proximity Read ↗

Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation.Semantic proximity Read ↗

Detection of Allele-Specific 3D Chromatin Interactions Using High-Resolution In-Nucleus 4C-seq.Semantic proximity Read ↗

CTCF binding at the <i>H19</i> imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to <i>Igf2</i>Semantic proximity Read ↗

CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop.Semantic proximity Read ↗

The role of CTCF in the organization of the centromeric 11p15 imprinted domain interactomeSemantic proximity Read ↗

A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele.Semantic proximity Read ↗

Three-dimensional conformation at the H19/Igf2 locus supports a model of enhancer trackingSemantic proximity Read ↗

The embryonic DNA methylation program modulates the <i>cis-</i> regulatory landscape via CTCF antagonismSemantic proximity Read ↗

Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexesSemantic proximity Read ↗

Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2.Semantic proximity Read ↗

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