Article
FOXP3 polymorphisms in type 1 diabetes and coeliac disease.
Journal of autoimmunity - 1 Sept 2006
Bjørnvold Marit, Amundsen Silja S, Stene Lars C, Joner Geir, Dahl-Jørgensen Knut, Njølstad Pål R, Ek Johan, Ascher Henry, Gudjònsdòttir Audur H, Lie Benedicte A, Skinningsrud Beate, Akselsen Hanne E, Rønningen Kjersti S, Sollid Ludvig M, Undlien Dag E
Abstract excerpt
The FOXP3 gene encodes a transcription factor thought to be essential for the development and function of T regulatory cells. Two previous studies have tested common polymorphisms in FOXP3 for association with type 1 diabetes (T1D) with conflicting results. The aim of our study was to see whether there is any evidence of association between the FOXP3 polymorphisms previously reported to be associated with T1D, in...
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