Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus.

Nature - 11 Oct 1990

Parry N, Fox G, Rowlands D, Brown F, Fry E, Acharya R, Logan D, Stuart D

Abstract excerpt

Changes resulting in altered antigenic properties of viruses nearly always occur on their surface and have been attributed to the substitution of residues directly involved in binding antibody. To investigate the mechanism of antigenic variation in foot-and-mouth disease virus (FMDV), variants that escape neutralization by a monoclonal antibody have been compared crystallographically and serologically with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antigens, Viral
Share to Capsid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Epitopes

Share to Genetic Variation

Share to Molecular Structure

Share to Protein Conformation

Source

Identifiers

PMID: 1699132
DOI: 10.1038/347569a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus.PMID 1699132Read ↗

Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity.Semantic proximity Read ↗

Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites.Semantic proximity Read ↗

Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67.Semantic proximity Read ↗

Genetic basis of antigenic variation in foot-and-mouth disease serotype A viruses from the Middle East.Semantic proximity Read ↗

Evaluation and Use of In-Silico Structure-Based Epitope Prediction with Foot-and-Mouth Disease VirusSemantic proximity Read ↗

Tracking the Antigenic Evolution of Foot-and-Mouth Disease VirusSemantic proximity Read ↗

Foot-and-mouth disease virus.Semantic proximity Read ↗

Analysis of flavivirus envelope proteins reveals variable domains that reflect their antigenicity and may determine their pathogenesis.Semantic proximity Read ↗

The structure and antigenicity of a type C foot-and-mouth disease virusSemantic proximity Read ↗

Sequence analysis of monoclonal antibody resistant mutants of type O foot and mouth disease virus: evidence for the involvement of the three surface exposed capsid proteins in four antigenic sites.Semantic proximity Read ↗

Antigenic variation of foot-and-mouth disease virus serotype ASemantic proximity Read ↗

Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.