Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies

Abstract excerpt

Foot-and-mouth disease (FMD) is an economically devastating and highly contagious viral disease of cloven-hoofed animals with a global distribution. The causative agent, FMD virus (FMDV) is a small non-enveloped RNA virus, belonging to the Aphthoviruses genus within Picornaviridae family (Tuthill et al., 2010). Control of FMD has been largely reliant on vaccinations with inactivated virus vaccines. However,...

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