Article
Abnormal melt curve profile during prothrombin 20210G --> A analysis due to the 20209C --> T variant.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2006
Dunn S Terence, Allen Richard A, Bates Francesca, McNamara Victoria, Comp Philip
Abstract excerpt
The common factor II 20210G --> A mutation, located in the 3'-untranslated region, is an important risk factor for the development of thromboembolic disorders, especially in Caucasians. A number of methods are employed for clinical laboratory diagnosis of this mutation, some of which are capable of detecting adjacent 3'-end sequence variations. We present results from an African deep vein thrombosis patient...
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