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Article

Inherited erythermalgia: limb pain from an S4 charge-neutral Na channelopathy.

Neurology - 14 Nov 2006

Choi Jin-Sung, Dib-Hajj Sulayman D, Waxman Stephen G

Abstract excerpt

BACKGROUND: Inherited erythermalgia (also termed "erythromelalgia"), characterized by episodic burning pain in the distal extremities evoked by warmth, has been causally linked with mutations of the Na(v)1.7 sodium channel, which is preferentially expressed in nociceptors. Thus far, Na(v)1.7 mutations within intracellular linker parts of the channel have been physiologically characterized. OBJECTIVE: To...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16988069
DOI: 10.1212/01.wnl.0000231514.33603.1e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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