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Article

Association of the methylenetetrahydrofolate reductase A1298C but not the C677T single nucleotide polymorphism with sickle cell disease in Bahrain.

Hemoglobin - 1 Jan 2006

Al-Absi Iman K, Al-Subaie Abeer M, Ameen Ghada, Mahdi Najat, Mohammad Akbar Mohsin, Fawaz Naglaa A, Almawi Wassim Y

Abstract excerpt

The association of methylenetetrahydrofolate reductase (MTHFR) gene mutations, C677T and A1298C, together with changes in homocysteine (Hcy) levels was investigated in 106 sickle cell disease patients and 156 healthy controls from Bahrain. The mutation analysis was done by restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR). While the frequencies of the mutant alleles C677T and A1298C...

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Source

Identifiers

PMID: 16987799
DOI: 10.1080/03630260600867958

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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