Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.

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Article

Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.

Journal of lipid research - 1 Jul 1990

Xu C F, Tikkanen M J, Huttunen J K, Pietinen P, Bütler R, Humphries S, Talmud P

Abstract excerpt

We have investigated the insertion/deletion polymorphism in the signal peptide region of the apoB gene in 106 Finnish individuals from North Karelia. The relative frequency of the insertion allele in this sample was 0.73. Strong linkage disequilibrium was detected between this apoB insertion/deletion polymorphism and the Ag(c/g) epitope pair of apoB, while weak linkage disequilibrium was detected between the...

Topics

Adult
Amino Acid Sequence
Analysis of Variance
Apolipoproteins B
Base Sequence
Dietary Fats
Epitopes
Female
Genes
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Male

Middle Aged

Molecular Sequence Data

Mutation

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 1698214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1698214-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.PMID 1698214Read ↗

An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene.Semantic proximity Read ↗

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