Article
An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene.
Human genetics - 1 Mar 1990
Visvikis S, Chan L, Siest G, Drouin P, Boerwinkle E
Abstract excerpt
In this communication we report the genetic properties of an insertion/deletion polymorphism in the signal peptide of the human apolipoprotein B (apo b) gene. There are two alleles of the apo B signal peptide; one codes for a peptide 27 amino acids in length and the other a peptide only 24 amino acids in length. Using the polymerase chain reaction the difference of nine nucleotides between the two alleles is...
Topics
- Alleles
- Apolipoproteins B
- Base Sequence
- Chromosome Deletion
- Genotype
- Humans
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Protein Sorting Signals