Article
The ins/del polymorphism in the signal sequence of apolipoprotein B has no effect on lipid parameters.
Clinica chimica acta; international journal of clinical chemistry - 30 Sept 1993
Gaffney D, Freeman D J, Shepherd J, Packard C J
Abstract excerpt
The 'ins/del' polymorphism in the signal sequence of apolipoprotein B alters the hydrophobicity of the signal sequence and therefore would be expected to affect the rate of production of apolipoprotein B (apo B) and the plasma concentrations of lipoproteins containing this apolipoprotein. We sought evidence for an association with plasma lipid levels and this polymorphism in two studies, one using a normal...
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