Article
Inhibition of CD1d1-mediated antigen presentation by the vaccinia virus B1R and H5R molecules.
European journal of immunology - 1 Oct 2006
Webb Tonya J Roberts, Litavecz Roberta A, Khan Masood A, Du Wenjun, Gervay-Hague Jacquelyn, Renukaradhya Gourapura J, Brutkiewicz Randy R
Abstract excerpt
Vaccinia virus (VV) has been most commonly used as the vaccine to protect individuals against the causative agent of smallpox (variola virus), but it also uses a number of strategies meant to evade or blunt the host's antiviral immune response. Natural killer T (NKT) cells are a subset of immunoregulatory CD1d-restricted T lymphocytes believed to bridge the innate and adaptive immune responses. It is shown here...
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