Article
delta-Globin gene structure and expression in the K562 cell line.
Hemoglobin - 1 Nov 2003
Poddie Daniela, Marongiu Maria F, Ferrari Silvia Cigliuti, Porcu Susanna, Ristaldi Maria S
Abstract excerpt
The delta-globin gene produces the delta chain of Hb A2 which represents less than 3% of the hemoglobin (Hb) in normal individuals. The delta-globin gene is also expressed in the human erythroleukemia cell line K562. The expression of the delta-globin gene in this cell line is unexpected since K562 shows an embryonic-fetal globin gene expression pattern with no expression of the adult beta-globin gene....
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