Article
Quantitation of N-acetyl-S-(9,10-dihydro-9-hydroxy-10-phenanthryl)-L-cysteine in human urine: comparison with glutathione-S-transferase genotypes in smokers.
Chemical research in toxicology - 1 Sept 2006
Upadhyaya Pramod, Rao Priyanka, Hochalter J Bradley, Li Zhong-Ze, Villalta Peter W, Hecht Stephen S
Abstract excerpt
There are major interindividual differences in carcinogenic polycyclic aromatic hydrocarbon (PAH) metabolism in humans, and it has been hypothesized that these differences may be related to cancer risk in smokers and other exposed people. One important pathway of PAH metabolism involves the detox...
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