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Article

Role of autophagy in the clearance of mutant huntingtin: a step towards therapy?

Molecular aspects of medicine - 1 Jan 2000

Ravikumar Brinda, Rubinsztein David C

Abstract excerpt

Macroautophagy (henceforth referred to simply as autophagy) is a bulk degradation process involved in the clearance of long-lived proteins, protein complexes and organelles. A portion of the cytosol, with its contents to be degraded, is enclosed by double-membrane structures called autophagosomes...

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Identifiers

PMID: 16973207
DOI: 10.1016/j.mam.2006.08.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16973207-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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