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Article

CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interaction.

Nucleic acids research - 1 Jan 2006

Lin Chih-Yin, Navarro Sonia, Reddy Sita, Comai Lucio

Abstract excerpt

High levels of rRNA synthesis by RNA polymerase I are important for cell growth and proliferation. In vitro studies have indicated that the formation of a stable complex between the HMG box factor [Upstream binding factor (UBF)] and SL1 at the rRNA gene promoter is necessary to direct multiple rounds of Pol I transcription initiation. The recruitment of SL1 to the promoter occurs through protein interactions with...

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Share to Casein Kinase II
Share to Binding Sites
Share to Genes, rRNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphorylation

Share to Promoter Regions, Genetic

Share to Protein Structure, Tertiary

Share to RNA Polymerase I

Share to Transcription, Genetic

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Identifiers

PMID: 16971462
DOI: 10.1093/nar/gkl581
PMCID: PMC1635259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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