Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor.

American journal of physiology. Cell physiology - 1 May 2007

Lin C Huie, Platt Mark D, Ficarro Scott B, Hoofnagle Mark H, Shabanowitz Jeffrey, Comai Lucio, Hunt Donald F, Owens Gary K

Abstract excerpt

rRNA transcription is a fundamental requirement for all cellular growth processes and is activated by the phosphorylation of the upstream binding factor (UBF) in response to growth stimulation. Even though it is well known that phosphorylation of UBF is required for its activation and is a key step in activation of rRNA transcription, as yet, there has been no direct mapping of the UBF phosphorylation sites. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, Affinity
Share to Databases, Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocytes, Smooth Muscle

Share to Nanotechnology

Share to Peptide Mapping

Share to RNA Polymerase I

Share to Spectrometry, Mass, Electrospray Ionization

Share to Tandem Mass Spectrometry

Source

Identifiers

PMID: 17182730
DOI: 10.1152/ajpcell.00176.2006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor.PMID 17182730Read ↗

The Saccharomyces cerevisiae 60 S ribosome biogenesis factor Tif6p is regulated by Hrr25p-mediated phosphorylation.Semantic proximity Read ↗

Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylationSemantic proximity Read ↗

Regulation of upstream binding factor 1 activity by insulin-like growth factor I receptor signaling.Semantic proximity Read ↗

Phosphorylation of ribosomal protein S6 differentially affects mRNA translation based on ORF length.Semantic proximity Read ↗

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF.Semantic proximity Read ↗

Histone H3 serine 57 and lysine 56 interplay in transcription elongation and recovery from S-phase stress.Semantic proximity Read ↗

Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease.Semantic proximity Read ↗

ERK modulates DNA bending and enhancesome structure by phosphorylating HMG1-boxes 1 and 2 of the RNA polymerase I transcription factor UBF.Semantic proximity Read ↗

Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth.Semantic proximity Read ↗

Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing.Semantic proximity Read ↗

Characterization of a fission yeast subunit of an RNA polymerase I essential transcription initiation factor, SpRrn7h/TAF(I)68, that bridges yeast and mammals: association with SpRrn11h and the core ribosomal RNA gene promoter.Semantic proximity Read ↗

Autophosphorylation of threonine 485 in the activation loop is essential for attaining eIF2alpha kinase activity of HRI.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.