Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein kinase CK2 regulates the dimerization of histone deacetylase 1 (HDAC1) and HDAC2 during mitosis.

The Journal of biological chemistry - 7 Jun 2013

Khan Dilshad H, He Shihua, Yu Jenny, Winter Stefan, Cao Wenguang, Seiser Christian, Davie James R

Abstract excerpt

Histone deacetylase 1 (HDAC1) and HDAC2 are components of corepressor complexes that are involved in chromatin remodeling and regulation of gene expression by regulating dynamic protein acetylation. HDAC1 and -2 form homo- and heterodimers, and their activity is dependent upon dimer formation. Phosphorylation of HDAC1 and/or HDAC2 in interphase cells is required for the formation of HDAC corepressor complexes. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Casein Kinase I
Share to Chromosomes, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Co-Repressor Proteins

Share to HEK293 Cells

Share to HeLa Cells

Share to Histone Deacetylase 1

Share to Mitosis

Share to Protein Multimerization

Source

Open in PubMed Open full text

Identifiers

PMID: 23612983
DOI: 10.1074/jbc.M112.440446
PMCID: PMC3675587

Genes

HDAC1
HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein kinase CK2 regulates the dimerization of histone deacetylase 1 (HDAC1) and HDAC2 during mitosis.PMID 23612983Read ↗

Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation.Semantic proximity Read ↗

CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activitySemantic proximity Read ↗

NudC deacetylation regulates mitotic progression.Semantic proximity Read ↗

CK2 phosphorylation of Bdp1 executes cell cycle-specific RNA polymerase III transcription repression.Semantic proximity Read ↗

A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.Semantic proximity Read ↗

Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylationSemantic proximity Read ↗

Plk1 regulates mutant IDH1 enzyme activity and mutant IDH2 ubiquitination in mitosis.Semantic proximity Read ↗

Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA.Semantic proximity Read ↗

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization.Semantic proximity Read ↗

CKAP2 phosphorylation by CDK1/cyclinB1 is crucial for maintaining centrosome integrity.Semantic proximity Read ↗

Genome-wide expression screens indicate a global role for protein kinase CK2 in chromatin remodeling.Semantic proximity Read ↗

Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatin dissociation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.