Article
Assessing the predictive accuracy of hMLH1 and hMSH2 mutation probability models.
Journal of genetic counseling - 1 Oct 2006
Jasperson Kory W, Lowstuter Katrina, Weitzel Jeffrey N
Abstract excerpt
Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by a susceptibility to colorectal and extra-colonic cancers. Several guidelines exist for the identification of families suspected of having HNPCC, however these guidelines lack adequate sensitivity and specificity. In an attempt...
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