Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations.

doi:10.1111/j.1572-0241.2006.00522.x

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Article

Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations.

The American journal of gastroenterology - 1 May 2006

Rodríguez-Moranta Francisco, Castells Antoni, Andreu Montserrat, Piñol Virgínia, Castellví-Bel Sergi, Alenda Cristina, Llor Xavier, Xicola Rosa M, Jover Rodrigo, Payá Artemio, Bessa Xavier, Balaguer Francesc, Cubiella Joaquin, Argüello Lidia, Morillas Juan Diego, Bujanda Luis

Abstract excerpt

UNLABELLED: Identification of individuals who should undergo hereditary nonpolyposis colorectal cancer (HNPCC) genetic testing is a critical and difficult issue. For this purpose, the National Cancer Institute outlined a set of recommendations, the Bethesda guidelines, which have recently been revised. OBJECTIVE: To compare the clinical performance of original and revised Bethesda guidelines for the detection of...

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PMID: 16696788
DOI: 10.1111/j.1572-0241.2006.00522.x

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MLH1
MSH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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