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Article

No association of the C677T methylenetetrahydrofolate reductase polymorphism with schizophrenia.

Psychiatric genetics - 1 Oct 2006

Philibert Robert, Gunter Tracy, Hollenbeck Nancy, Adams William J, Bohle Phillip, Packer Hans, Sandhu Harinder

Abstract excerpt

Some serological and genetic studies have suggested that alterations in folate metabolism are associated with increased vulnerability to schizophrenia. In particular, these findings are most striking for the role of a putatively functional variant (C677T) in the methylenetetrahydrofolate reductase (MTHFR) gene. To test the hypothesis that the T allele and the TT genotype are risk factors for psychosis, we...

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Source

Identifiers

PMID: 16969279
DOI: 10.1097/01.ypg.0000242192.28526.fa

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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