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Article

EWS-FLI1 and Ewing's sarcoma: recent molecular data and new insights.

Cancer biology & therapy - 1 Jan 2000

Ladanyi Marc

Abstract excerpt

The EWS-FLI1 fusion resulting from the specific t(11;22)(q24;q12) of Ewing's sarcoma was the first sarcoma gene fusion to be cloned, a decade ago. Moving from the cloning of this oncogenic chimeric transcription factor to the further elucidation of its pathogenetic mechanisms has revealed new com...

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Share to Cyclin-Dependent Kinase Inhibitor p16
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Share to Oncogene Proteins, Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Protein c-fli-1

Share to RNA-Binding Protein EWS

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Source

Identifiers

PMID: 12432241

Genes

FLI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12432241-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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