Article
Molecular Genetics of Early- and Late-Onset Alzheimer's Disease.
Current gene therapy - 1 Jan 2021
Uddin Md Sahab, Hasana Sharifa, Hossain Md Farhad, Islam Md Siddiqul, Behl Tapan, Perveen Asma, Hafeez Abdul, Ashraf Ghulam Md
Abstract excerpt
Alzheimer's disease (AD) is the most common form of dementia in the elderly and this complex disorder is associated with environmental as well as genetic factors. Early-onset AD (EOAD) and late-onset AD (LOAD, more common) are major identified types of AD. The genetics of EOAD is extensively understood, with three gene variants such as APP, PSEN1, and PSEN2 leading to the disease. Some common alleles, including...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.