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Article

Bone marrow-transforming activity of linker insertion mutants of Abelson murine leukemia virus.

Oncogene - 1 Nov 1992

Hevezi P, Alin K, Rees-Jones R, Goff S P

Abstract excerpt

Two sets of mutants of the Abelson murine leukemia virus, generated by linker insertion mutagenesis of a cloned proviral DNA, were tested for their ability to transform bone marrow cultures in vitro. All the viruses retained an intact tyrosine kinase domain and were competent for transformation of NIH3T3 fibroblasts in culture. One series contained 12-bp linker insertions in the regions flanking the kinase...

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Share to B-Lymphocytes
Share to Cell Transformation, Neoplastic
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mutagenesis, Insertional

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Identifiers

PMID: 1437154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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