Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma protein S activity correlates with protein S genotype but is not sensitive to identify K196E mutant carriers.

Journal of thrombosis and haemostasis : JTH - 1 Sept 2006

Kimura R, Sakata T, Kokubo Y, Okamoto A, Okayama A, Tomoike H, Miyata T

Abstract excerpt

BACKGROUND: Protein S (PS) is an anticoagulant protein that functions as a cofactor for activated protein C (APC), and congenital PS deficiency is a well-known risk factor for the development of deep vein thrombosis (DVT). Recently, we and others identified the K196E missense mutation in the second epidermal growth factor-like domain of PS as a genetic risk factor for DVT in the Japanese population. The incidence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Genetic Carrier Screening

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Molecular Epidemiology

Share to Mutation, Missense

Share to Protein S

Share to Sex Factors

Source

Identifiers

PMID: 16961608
DOI: 10.1111/j.1538-7836.2006.02071.x

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma protein S activity correlates with protein S genotype but is not sensitive to identify K196E mutant carriers.PMID 16961608Read ↗

Protein S abnormalities: A diagnostic nightmareSemantic proximity Read ↗

ELISA-Based Detection System for Protein S K196E Mutation, a Genetic Risk Factor for Venous Thromboembolism.Semantic proximity Read ↗

Protein S deficiency.Semantic proximity Read ↗

Protein C and protein S deficiencies: similarities and differences between two brothers playing in the same game.Semantic proximity Read ↗

Molecular basis of protein S deficiency.Semantic proximity Read ↗

Genetic risk factors for deep vein thrombosis among Japanese: importance of protein S K196E mutation.Semantic proximity Read ↗

Molecular basis of protein S deficiency in ChinaSemantic proximity Read ↗

Protein S–K196E mutation as a genetic risk factor for deep vein thrombosis in Japanese patientsSemantic proximity Read ↗

Protein S deficiency: a clinical perspective.Semantic proximity Read ↗

Normal functional protein S activity does not exclude protein S deficiency.Semantic proximity Read ↗

Protein S type III deficiency is no risk factor for venous and arterial thromboembolism in 168 thrombophilic families: a retrospective study.Semantic proximity Read ↗

Racial differences in protein S Tokushima and two protein C variants as genetic risk factors for venous thromboembolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.